Annual General Shareholders' Meeting 2006

Dear Shareholders,

We invite you to attend the Annual General Shareholders’ Meeting of Epigenomics AG to be held on Monday, July 10, 2006 at 11.00 a.m., on the premises of Deutsche Bank, Unter den Linden 13–15 (entrance Charlottenstraße), 10117 Berlin.

Invitation to the Annual General Shareholders' Meeting 2006
of Epigenomics AG 

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Counterproposals

All proposals which are submitted by shareholders in connection with the agenda for the General Meeting on July 10, 2006 and which have to be made accessible will be published without delay here.

Counterproposal as of June 23, 2006

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Statement regarding the counter-proposal

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Review

Epigenomics AG held its 2nd Annual General Shareholders' Meeting in Berlin with about 100 shareholders, its representatives and guests on July 10, 2006. The presence before the voting was at 11,491,458 individual shares, equivalent to 70.06 % of the authorized capital.

All TOPs were agreed to. The counterproposal of June 23, 2006 was denied. More detailed information are available on our German website.